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由于人口的高龄化,近来骨质疏松症的发生率急骤增长多见于中年以后的女性。据认为它是人类所患疾病中频率最高的,目前在日本有500万以上病人。所谓骨质疏松症就是骨量的减少,它不同于骨软化症和纤维性骨炎,其成分大致保持在正常水平。可以认为,由于骨的吸收与形成的平衡被破坏,骨吸收占优势的结果造成骨量减少。骨的吸收和形成是受到全身及局部的多种因素的调节,因此,骨质疏松的原因也并不是单纯的,可以大致分为遗传性、物理性、代谢性及免疫性等因素。目前,本病的药物疗法主要倾向于代谢性因素,
Due to the aging population, the recent rapid increase in the incidence of osteoporosis is more common in women after middle age. It is thought to have the highest frequency of disease in humans, and currently there are more than 5 million patients in Japan. The so-called osteoporosis is the reduction of bone mass, which is different from osteomalacia and fibrositis, its components are generally maintained at normal levels. It is believed that as a result of the destruction of the balance between absorption and formation of bone, bone resorption results in a decrease in bone mass. Bone absorption and formation are regulated by a variety of factors, both systemic and local. Therefore, the causes of osteoporosis are not simple and can be roughly divided into genetic, physical, metabolic and immune factors. At present, the drug therapy of this disease mainly tends to metabolic factors,