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观察甲基硝基亚硝基胍（MNNG）诱发大鼠胃癌过程中淋巴细胞转化率的变化及大蒜对其的影响，发现癌前病变、粘膜内癌及浸润癌各组之间及各组与正常组之间淋巴细胞转化率差异有显著性（P＜0．01），提示在MNNG诱癌过程中淋巴细胞免疫功能的降低与胃癌的发生发展有关系。而大蒜预防组、治疗组与MNNG组之间淋巴细胞转化率差异有显著性（P＜0．01），同时诱癌率明显下降，认为大蒜可抑制MNNG诱发实验性胃癌的发生，其机理与大蒜提高诱癌过程中机体细胞免疫功能有关。
Observed the changes of lymphocyte transformation rate induced by methylnitrosoguanidine (MNNG) in rat gastric cancer and the effect of garlic on it, and found that precancerous lesions, intramucosal cancer and invasive cancer between each group and each group. The difference in lymphocyte conversion between the normal group was significant (P<0.01), suggesting that the decrease of lymphocyte immune function in the process of MNNG carcinogenesis is related to the occurrence and development of gastric cancer. The difference in lymphocyte conversion between the garlic prevention group, the treatment group and the MNNG group was significant (P<0.01), and the cancer-inducing rate was significantly decreased. It is believed that garlic can inhibit the occurrence of experimental gastric cancer induced by MNNG, and its mechanism is Garlic improves the cellular immune function in the process of carcinogenesis.