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与DTP有关的异常反应主要发生在出生后六个月内,因而,人们考虑推迟DTP免疫年龄。推荐的程序系将现行程序中DTP免疫的时间(2、4和6月龄)推迟到8、10和12月龄。对370万名儿童进行队列调查,每个队列可分为<2月龄、2～6月龄,7～12月龄和13～47月龄组,随访4年。为检验效益-危险性分析对百日咳发病率、菌苗相关脑病发生率、癫痫发作的发生率等主要变化因素分析的敏感性,设了一般情况、最佳情况和最坏情况组,借以评价推荐程序。对一般情况组的分析结果表明,采用推
DTP-related abnormalities occur mainly within six months after birth, and therefore, people consider postponing DTP immunization age. The recommended procedure is to postpone the duration of DTP immunization (2, 4 and 6 months of age) in current procedures to 8, 10 and 12 months of age. A cohort of 3.7 million children was enrolled in the cohort. Each cohort was divided into 2 months, 2 to 6 months, 7 to 12 months and 13 to 47 months of age, followed up for 4 years. To test the effectiveness of - risk analysis for the incidence of pertussis, the incidence of vaccine-related encephalopathy, the incidence of seizures and other major changes in the sensitivity of the factors that set the general situation, the best situation and the worst case group to evaluate the recommended program. Analysis of the general case group showed that the use of push