论文部分内容阅读
目的分析经呼吸道吸入兼皮肤吸收百草枯所致中毒的临床特点。方法对6例经呼吸道吸入兼皮肤吸收百草枯所致中毒患者临床资料进行回顾性分析。结果患者主要经呼吸道吸入兼皮肤吸收百草枯发病;临床表现有口腔、咽部、鼻腔及眼部刺激症状、溃疡或炎症表现,以及胸闷、气促、咳嗽等呼吸系统症状,并伴不同程度的肺、肝、肾、心多脏器损伤,以肺损伤最为严重;肺部感染为主要并发症;早期、足量糖皮质激素冲击治疗有效;6例患者均存活。结论呼吸道吸入兼皮肤吸收百草枯导致的中毒,早期使用糖皮质激素及采取抗氧化、抗纤维化等综合治疗措施,积极防治肺部感染,保护肝、肾和心功能是提高此类患者存活率的关键。
Objective To analyze the clinical characteristics of paraquat poisoning caused by respiratory inhalation and skin absorption. Methods The clinical data of 6 cases of poisoning caused by respiratory inhalation and skin absorption paraquat were retrospectively analyzed. Results The patient mainly inhaled paraquat through the respiratory tract and the skin. The clinical manifestations were oral, pharyngeal, nasal and ocular irritation, ulcer or inflammation, and chest tightness, shortness of breath, cough and other respiratory symptoms, with varying degrees of Lung, liver, kidney, heart and multiple organ injury, with the most severe lung injury; pulmonary infection as the main complication; Early, adequate glucocorticoid impact treatment; 6 patients were alive. Conclusion Respiratory tract inhalation and skin absorption caused by paraquat poisoning, early use of glucocorticoids and take anti-oxidation, anti-fibrosis and other comprehensive treatment measures, active prevention and treatment of pulmonary infection, protect liver, kidney and heart function is to improve the survival rate of such patients key.