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对7例接受机械通气的重症中风患者氧动力学指标进行研究。发现中风后第3天时系统氧输送(DO2)与中风第1天相比显著增加(588±254mlmin-1/m2比448±206mlmin-1/m2),而心脏指数(CI)和动脉血氧含量(CaO2)却无相应的变化;中风后第7天脑组织(51%±6%比33%±17%)和系统的氧摄取率(ER,53%±22%比28%±13%)与中风后第1天相比显著增高,以满足氧消耗(VO2)的增加(230±153mlmin-1/m2比114±49mlmin-1/m2)。3例有并发症的中风患者存在氧耗的病理性氧供依赖性。因此推论:由CI和CaO2计算所得的DO2较血流动力学指标的变化可能更敏感;已经治疗7天的中风患者仍存在较高的ER,可能预后较差;没有严重并发症的中风患者是否存在氧耗的病理性氧供依赖性有待进一步研究
Oxygen kinetics indices of 7 stroke patients undergoing mechanical ventilation were studied. Systemic oxygen delivery (DO2) was significantly increased at day 3 post stroke (588 ± 254 ml min-1 / m2 vs 448 ± 206 ml min-1 / m2) compared with day 1 of stroke, whereas cardiac index (CI) and arterial oxygen content (51% ± 6% vs 33% ± 17%) and systemic oxygen uptake rate (ER, 53% ± 22% vs. 28% ± 13%) on the seventh day after stroke Significantly higher than day 1 after stroke to meet the increase in oxygen consumption (230 ± 153 ml min-1 / m2 vs 114 ± 49 ml min-1 / m2). Three patients with complications of stroke had oxygen-dependent pathological oxygen dependence. Therefore, the corollary is that DO2 calculated from CI and CaO2 may be more sensitive than changes in hemodynamic indices; patients with stroke that have been on treatment for 7 days still have higher ERs and may have a worse prognosis; whether stroke patients with no serious complications are Pathological oxygen-dependent dependence of oxygen consumption is for further study