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[目的]分析上海市浸润性子宫颈癌的死亡特征及其趋势。[方法]利用上海市死因监测系统收集的子宫颈癌死亡病例资料,运用年度变化百分比对上海市1974—2011年浸润性子宫颈癌死亡率的时间趋势进行分析。[结果]上海是浸润性子宫颈癌死亡率相对较低的地区,2007—2011年的粗死亡率为2.48/10万,标化死亡率为1.26/10万,市区死亡率均高于郊区,与1974—1978年相比,死亡中位年龄提前7岁,30-44岁的死亡率高于1974—1978年同年龄组值。1974至2011年,浸润性子宫颈癌标化死亡率共下降84.04%。阶段趋势分析显示,自1999年始,上海市区浸润性子宫颈癌的标化死亡率由下降转为上升,郊区女性的死亡率由降转为升的时间点为1997年,自1993年起,35-44岁年龄段人群死亡率就开始由下降转为上升。[结论]上海市浸润性子宫颈癌死亡率处于较低水平;子宫颈癌死亡年轻化趋势明显。从1999年开始,浸润性子宫颈癌标化死亡率由下降转为上升,主要由于55岁以上女性死亡率上升所致。未来应加强对子宫颈癌的筛查普及,尤其是年轻女性,同时应加强规范化诊治,降低子宫颈癌的死亡率。
[Objective] To analyze the characteristics and trends of death in invasive cervical cancer in Shanghai. [Method] Using the data of death from cervical cancer collected by the Shanghai cause of death monitoring system, the time trend of the mortality of invasive cervical cancer from 1974 to 2011 in Shanghai was analyzed by using the annual percentage change. [Results] Shanghai was a relatively low mortality rate of invasive cervical cancer with a crude death rate of 2.48 / lakh in 2007-2011 and a normalized death rate of 1.26 / lakh. The urban mortality rate was higher than that in the suburbs, The median death toll was 7 years earlier than in 1974-1978, and the 30-44 mortality rate was higher than the 1974-1978 same age group. From 1974 to 2011, the standardized mortality of invasive cervical cancer decreased by 84.04%. Phase trend analysis showed that from 1999 onwards, the standardized mortality rate of invasive cervical cancer in Shanghai increased from decline to rise, and the death rate of suburban women dropped from rising to rising at 1997. Since 1993, 35 -44 age group population mortality began to decline from rising to rising. [Conclusion] The mortality rate of invasive cervical cancer in Shanghai is at a low level. The death of cervical cancer is more younger. Since 1999, the standardized mortality rate of invasive cervical cancer has been changed from decline to increase, mainly due to the rising mortality rate among women over 55 years of age. The future should strengthen the popularity of cervical cancer screening, especially young women, should also strengthen the standardization of diagnosis and treatment to reduce the mortality rate of cervical cancer.