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近十余年来,国内外学者对人类及其某些动物的淋巴细胞与绵羊红细胞(简称SR-BC)自然结合这一现象作了广泛的研究.这些工作包括E玫瑰花实验技术的改进,实际应用和理论探讨等方面.在实际应用方面,进行了影响实验结果诸因素的研究、E玫瑰花各种实验技术的临床应用并试图将其作为细胞免疫的指标而用于疗效观察以及应用E玫瑰花实验鉴定某些生物制剂(如抗淋巴细胞血清、胸腺素和转移因子等)的生物活性.由于E玫瑰花实验操作不易控制和某些理论问题尚未解决,E玫瑰花的实际应用研究难以深入,有关文献报告日趋减少.在理论探讨方面,以下问题已有报导尚无争议:
In recent ten years, scholars at home and abroad have made extensive research on the natural combination of lymphocytes and sheep erythrocytes (referred to as SR-BC) in humans and some of their animals.These work include the improvement of E-rose experimental technology, Practical application and theory discussion, etc. In practical application, the research on various factors influencing the experimental results has been carried out and the clinical application of various experimental techniques of E-rose has been carried out and tried to be used as an indicator of the cellular immunity for the observation of therapeutic effects and the application of E Rose experiments have identified the biological activity of certain biological agents such as anti-lymphocyte serum, thymosin and transfer factor, etc. Due to the difficult to control experimental operation of E-rose and some theoretical problems have not been solved, the practical application of E-rose is difficult to study In-depth, the relevant literature reports declining .In the theoretical discussion, the following issues have been reported without controversy: