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5例反复发作室上性心动过速患儿均对毛地黄治疗不满意,年龄3周～11岁,其中4例作了心导管检查,1例3周婴儿卵圆孔未闭外,余3例无异常。给予口服心得安,7～14mg/kg/日(常用量为1～4mg/kg/日)治疗后所有病例均获得满意效果,室上性心动过速消失,仅1例以后在发烧时仍偶有发作,在服药期间无明显副作用。电生理学检查发现3例为隐匿性预激症候群(右 Keut 氏束1例,左 Keut 氏束2例),另一例有房室结二路通道(dual A-V nodalpathways)。随诊8个月至2年。患儿服药期间均测了心得安血浆浓度,最高值为118～250(平均159)ng/ml。
5 cases of recurrent supraventricular tachycardia in children were not satisfied with the treatment of WUD, aged 3 weeks to 11 years, of which 4 cases were catheterized, 1 case of 3-week-old baby patent foramen ovale, more than 3 No exception cases. Given oral propranolol, 7 ~ 14mg / kg / day (daily dose of 1 ~ 4mg / kg / day) after treatment in all cases were satisfactory results, supraventricular tachycardia disappeared, only 1 case even after the fever even A seizure, no significant side effects during the medication. Electrophysiological examination revealed three cases of occult pre-shock syndrome (right Keut’s bundle, left Keut’s bundle in 2 cases) and the other with dual A-V nodalpathways. Followed up for 8 months to 2 years. Measles plasma concentrations were measured during treatment in children, the highest value of 118 to 250 (average 159) ng / ml.