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目的了解浙江省内科门诊人群胃食管反流病的患病率,分析与之相关的危险因素。方法流行病学调查采用整体随机抽样、反流性疾病问卷(reflex diagnostic questionnaire.RDQ)调查方式,并采用多种统计学方法进行统计分析。结果浙江省内科门诊人群胃食管反流病的初筛患病率为7.28%,95%可信区间为6.87%～7.69%。不同性别、年龄、体力劳动强度、婚姻状况间胃食管反流病患病率差异有统计学意义(P<0.05)。进食过饱、常饮酸性饮料、常食辛辣食物、油腻食物、常饮浓茶、常进甜食、吸烟、饮酒、便秘者胃食管反流病患病率明显升高,差异有统计学意义(P<0.01)。单因素Logistic回归分析发现:性别、年龄、体力劳动强度、是否上夜班、婚姻状况是胃食管反流病的危险因素;多因素Logistic回归分析发现:年龄、是否上夜班、体力劳动强度、婚姻状况、进食过饱、常食油腻食物、常饮浓茶、常进甜食、便秘等可能是危险因素。结论问卷调查表是临床诊断胃食管反流病的一种简单、有效的方法。胃食管反流病有众多危险因素,临床上需引起高度重视。
Objective To understand the prevalence of gastroesophageal reflux disease among medical outpatients in Zhejiang Province and to analyze the risk factors associated with it. Methods Epidemiological survey using the whole random sampling, reflex disease questionnaire (reflex diagnostic questionnaire.RDQ) survey methods, and using a variety of statistical methods for statistical analysis. Results The prevalence of gastroesophageal reflux disease in Zhejiang outpatient population was 7.28%. The 95% confidence interval was 6.87% -7.69%. The prevalence of gastroesophageal reflux disease among different genders, ages, manual labor intensity and marital status was significantly different (P <0.05). Eating too much, often drink acidic drinks, eat spicy foods, greasy food, often drink tea, often into the sweets, smoking, drinking, constipation, gastroesophageal reflux disease prevalence was significantly increased, the difference was statistically significant (P <0.01). Univariate Logistic regression analysis showed that gender, age, manual labor intensity, night shift and marital status were the risk factors of gastroesophageal reflux disease. Multivariate Logistic regression analysis showed that age, night shift, manual labor intensity, marital status , Eating too much, often eat greasy food, often drink tea, often into the sweets, constipation may be a risk factor. Conclusion The questionnaire is a simple and effective method to diagnose gastroesophageal reflux disease clinically. Gastroesophageal reflux disease has many risk factors, the clinical need to be highly valued.