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目的观察药用炭片联合甲巯咪唑片治疗Graves病患者的疗效。方法回顾性分析我科门诊193例Graves病患者,随机分为单纯服用甲巯咪唑组(对照组),药用炭片联合甲巯咪唑片组(治疗组),比较两组疗效。结果两组患者治疗后甲状腺毒症缓解时间、FT3、FT4的下降差异有统计学意义(P<0.05),但治疗组明显优于对照组,差异有统计学意义(P<0.01)。结论药用炭片无明显毒副作用,联合甲巯咪唑片治疗Graves病患者疗效显著,值得临床研究应用。
Objective To observe the efficacy of medicinal carbon tablets combined with methimazole tablets in the treatment of patients with Graves’ disease. Methods A retrospective analysis of 193 outpatients with Graves’ disease was randomly divided into simple methimazole group (control group), medicinal carbon tablet and methimazole group (treatment group), and the curative effect was compared between the two groups. Results After treatment, the relief time of thyrotoxicosis, FT3 and FT4 decreased significantly in both groups (P <0.05), but the treatment group was significantly better than the control group, the difference was statistically significant (P <0.01). Conclusion The medicinal charcoal tablets have no obvious side effects. The combination of methimazole tablets in the treatment of patients with Graves’ disease has significant curative effect and is worthy of clinical application.