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用体重1.8—2.9公斤的24只封闭群新西兰白兔,随机分成三组,每组8只。第一组腹腔注射无热原生理盐水5ml/kg,作为对照;第二组腹腔注射高压(126℃,30分钟)灭菌牛奶5ml/kg;第三组与第二组同样腹腔注射牛奶一小时后针刺百会穴,针刺半小时后,间断通电。通电5分钟即停止通电10分钟,共通电6次。注射前2小时及注射后3.5小时内,每隔10分钟测一次直肠温度。然后比较各组腹腔注射后3.5小时的体温反应指数(TRI3.5)的均数与体温反应高峰(△T)的均数。实验结果如下:TRI3.5的(?)±SD,为:第一组0.22±0.27;第二组3.40±2.39;第三组0.63±0.52;△T的(?)±SD为:第一组0.13±018℃;第二组1.14±0.39℃,第三组0.41±0.34℃。经F检验与Q检验比较各组均数,均为P<0.01。结果表明间断电针能明显抑制无菌乳汁腹膜炎性发热,从而也说明无菌乳汁腹膜炎性发热是对针刺疗法敏感的发热模型。适用于实验治疗及其原理的研究。
Twenty-four closed New Zealand white rabbits weighing 1.8-2.9 kg were randomly divided into three groups of 8 rabbits. The first group was injected intraperitoneally with 5ml/kg of non-pyrogenic saline, as a control; the second group was given intraperitoneal injection of high-pressure (126°C, 30 minutes) sterilized milk 5ml/kg; the third group was injected intraperitoneally with milk for one hour as in the second group. After acupuncturing Bahui, acupuncture will be interrupted after half an hour. The power is turned on for 5 minutes and the power is turned off for 10 minutes. The power is turned on 6 times. The rectal temperature was measured every 10 minutes 2 hours before injection and 3.5 hours after injection. Then, the mean of body temperature response index (TRI3.5) and body temperature response peak (△T) after 3.5 hours after intraperitoneal injection were compared. The experimental results are as follows: (3.5) ± SD for TRI3.5: 0.22 ± 0.27 for the first group; 3.40 ± 2.39 for the second group; 0.63 ± 0.52 for the third group; ± (SD) ± SD for the △T: Group 1 0.13±018°C; second group 1.14±0.39°C, third group 0.41±0.34°C. The mean of each group was compared by F-test and Q-test, all P<0.01. The results showed that interrupted electroacupuncture can significantly inhibit the peritonitis fever of aseptic milk, which also shows that sterile milk peritoneal inflammatory fever is a sensitive thermal model of acupuncture. It is suitable for the study of experimental treatment and its principle.