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目的研究应用颅脑计算机断层扫描(CT)对癫痫疾病进行诊断的临床价值。方法对104例可疑癫痫受检者的临床资料进行回顾性分析,所有纳入者均分别接受颅脑CT和脑电图检查。将随访结果记为金标准,观察两种方法对癫痫诊断的灵敏度、准确度、特异度、正确指数、阳性和阴性预测值,并对比两种方法关于癫痫病因诊断符合率的差异。结果随访结果显示,本组受试者中共有42例癫痫患者,构成比为40.38%;在所有患者中,颅脑CT和脑电图检查诊断异常者分别有40例、31例;在62例非癫痫患者中,颅脑CT和脑电图检查诊断异常者分别有2例、5例。颅脑CT诊断癫痫疾病的灵敏度、准确度、特异度、正确指数、阳性和阴性预测值分别为95.24%、96.15%、96.77%、92.01%、95.24%和96.77%,均明显高于脑电图检查的73.81%、84.62%、91.94%、65.75%、86.11%、83.82%。颅脑CT诊断癫痫病因总符合率为95.24%,远高于脑电图检查的73.81%,差异具有统计学意义(χ~2=7.372,P<0.05)。结论对可疑癫痫疾病者采用颅脑CT扫描检查,不仅可提高准确度,还可对病因进行准确诊断,价值较高。
Objective To study the clinical value of craniocerebral computed tomography (CT) in the diagnosis of epilepsy. Methods The clinical data of 104 suspicious epilepsy subjects were retrospectively analyzed. All the participants accepted CT and EEG examinations respectively. The follow-up results were recorded as the gold standard. The sensitivity, accuracy, specificity, correctness index, positive and negative predictive value of the two methods for the diagnosis of epilepsy were observed. The differences between the two methods in assessing the etiological diagnosis of epilepsy were compared. Results The follow-up results showed that there were 42 cases of epilepsy in this group, the constituent ratio was 40.38%. Among all the patients, the diagnosis of brain CT and EEG were abnormal in 40 cases and 31 cases, respectively. In 62 cases Non-epileptic patients, brain CT and EEG abnormalities were diagnosed in 2 cases, 5 cases. The sensitivity, accuracy, specificity, correctness index, positive and negative predictive value of CT in diagnosis of epilepsy were 95.24%, 96.15%, 96.77%, 92.01%, 95.24% and 96.77% respectively, which were significantly higher than that of EEG Check 73.81%, 84.62%, 91.94%, 65.75%, 86.11%, 83.82%. The total coincidence rate of brain CT diagnosis of epilepsy was 95.24%, much higher than 73.81% of the EEG examination, the difference was statistically significant (χ ~ 2 = 7.372, P <0.05). Conclusion CT scan of suspicious epilepsy patients using brain CT scan, not only can improve the accuracy, but also the exact diagnosis of the cause of high value.