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测定母血甲胎蛋白含量,用以筛选异常妊娠,尤其是开放性神经管缺损妊娠已成为一种产前诊断的常规方法,国外已普遍开展。我们对太原市孕妇血中甲胎蛋白含量增高与异常妊娠的关系作了前瞻性研究。对妊娠13~40周的1,439例孕妇,采用免疫扩散放射自显影法定量测定甲胎蛋白含量,并进行了随访。用1,395例出生健康单胎婴儿的母血甲胎蛋白含量绘制了正
Determination of maternal serum alpha-fetoprotein content, to screen for abnormal pregnancy, especially open neural tube defects in pregnancy has become a routine method of prenatal diagnosis, has been widely carried out abroad. We conducted a prospective study on the relationship between the increase of alpha-fetoprotein in pregnant women and the abnormal pregnancy in Taiyuan. A total of 1,439 pregnant women of 13 to 40 weeks of gestation were immunosuppressed with autoradiography to quantitatively determine the content of alpha-fetoprotein. The patients were followed up. Positive maternal plasma alpha-fetoprotein levels were calculated for 1,395 healthy, singleton birth-born infants