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本文测定了子宫内膜异位症患者血清、腹水中CA_(125)含量,并对异位组织行CA_(125)免疫组化染色,以了解CA_(125)在这类患者体内的变化。对象和方法:主诉不孕而行腹腔镜检查的34例患者中,子宫内膜异位症24例,另10例正常者作对照。24例子宫内膜异位症中,根据修正AFS分类,Ⅰ、Ⅱ期(轻度)18例,Ⅲ、Ⅳ期(重度)6例。卵泡期后期行腹腔镜检查,于检查前1日采血清标本,腹腔镜直视下取腹水标本。17例在腹腔镜直视下活检内膜异位组织。血清、腹水的CA_(125)含量测定用放射免疫法,组织中的用免疫组化染色确定CA_(125)存在。结果:子宫内膜异位症患者血清CA_(125)值,轻
In this paper, the content of CA 125 in serum and ascites of patients with endometriosis was determined, and CA 125 immunohistochemistry staining was performed on the ectopic tissues to understand the change of CA 125 in these patients. Subjects and Methods: Of the 34 patients who underwent laparoscopy for infertility, 24 were endometriosis and 10 were normal controls. In 24 cases of endometriosis, according to the revised AFS classification, Ⅰ, Ⅱ (mild) 18 cases, Ⅲ, Ⅳ (severe) 6 cases. Late laparoscopic follicular examination, the day before the examination of serum samples, laparoscopic ascites under direct vision specimens. 17 cases underwent laparoscopic biopsy of endometriosis. Serum, ascites CA_ (125) content was measured by radioimmunoassay, immunohistochemical staining in the tissue to determine the presence of CA_ (125). Results: Serum CA 125 in patients with endometriosis was mild