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目的:评价痰热清注射液联合头孢噻肟钠治疗小儿肺炎的临床疗效。方法:将110例确诊为肺炎的患儿随机分为对照组和观察组各55例,对照组单用头孢噻肟钠50~100 mg/(kg·d),观察组在对照组治疗基础上加用痰热清注射液0.3~0.5mg/(kg·d),均静脉滴注给药,每次滴注时间>60 min,连续用药7~10 d。两组对症支持治疗相同,治疗期间不应用其他抗生素。观察两组患儿治疗后症状体征改善情况,评价临床疗效及不良反应。结果:观察组总有效率为92.73%,高于对照组的81.82%(P<0.05)。两组患儿治疗后中医症状评分均降低(P<0.01),且观察组低于对照组(P<0.01)。两组患儿均未发生严重不良反应。结论:痰热清注射液联合头孢噻肟钠治疗小儿肺炎能够明显改善临床症状并提高临床疗效,值得临床推广应用。
Objective: To evaluate the clinical efficacy of Tanreqing Injection and Cefotaxime Sodium in the treatment of children pneumonia. Methods: One hundred and ten children diagnosed with pneumonia were randomly divided into control group and observation group (n = 55). The control group was treated with cefotaxime sodium 50 ~ 100 mg / (kg · d) only. The observation group was treated on the basis of the control group Add Tanreqing injection 0.3 ~ 0.5mg / (kg · d), were intravenously administered, each infusion time> 60 min, continuous medication 7 ~ 10 d. Symptomatic support treatment of the same two groups, not during treatment with other antibiotics. The improvement of symptoms and signs after treatment in both groups were observed, and the clinical efficacy and adverse reactions were evaluated. Results: The total effective rate in the observation group was 92.73%, which was higher than that in the control group (81.82%, P <0.05). The scores of TCM symptoms in both groups were decreased (P <0.01), and the observation group was lower than the control group (P <0.01). No serious adverse reactions occurred in both groups. Conclusion: Tanreqing injection combined with cefotaxime sodium in children with pneumonia can significantly improve clinical symptoms and improve clinical efficacy, it is worthy of clinical application.