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经过胃镜或消化道钡餐Ｘ线检查确诊的２０例慢性胃炎、十二指肠炎患儿，以间接酶联免疫吸附试验（ＥＬＩＳＡ）检测血清幽门螺杆菌（ＨＰ）抗体为阳性者，用放射免疫法进行血清胃泌素含量的测定。结果显示：血清胃泌素平均浓度明显高于正常对照组（Ｐ＜０．０１、０．０５），有显著差异。表明在ＨＰ感染时，血清胃泌素含量是增高的，这在慢性胃炎的发病机理中有着重要的作用，及时检测其含量对疾病的早期诊断具有一定的临床意义
Twenty patients with chronic gastritis and duodenitis diagnosed by endoscopy or digestive tract barium meal X-ray examination were detected by indirect enzyme-linked immunosorbent assay (ELISA) for serological Helicobacter pylori (HP) antibody. Radioimmunoassay Serum gastrin levels were measured. The results showed that: the average serum gastrin concentration was significantly higher than the normal control group (P <0.01, 0.05), a significant difference. This indicates that the serum gastrin level is increased during HP infection, which plays an important role in the pathogenesis of chronic gastritis. It is of clinical significance to diagnose the disease early