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据近期出版的《高血压》杂志刊登的一项研究结果报道,细胞粘附分子-1(ICAM-1)浓度升高和先兆子痫的某些特点有可能导致有先兆子痫病史的妇女增加患冠心病(CHD)的危险性。来自于英国格拉斯哥大学的 Ian A.Greer 博士及其同事指出,流行病学研究显示,孕妇患有先兆子痫与其以后发生冠心病的危险增加存在一定的关联;但该结论尚缺乏足够多的数据以解释这种相关性的机制。研究人员将1975～1985年间经初产的并有蛋白尿先兆子痫病史的40名妇女作为研究对象,使其与40名在妊娠时间、吸烟和当前体重指数方面
A recent study published in the journal Hypertension reported that elevated concentrations of cell adhesion molecule-1 (ICAM-1) and certain features of pre-eclampsia may lead to an increase in women with a history of preeclampsia Risk of coronary heart disease (CHD). Ian A. Greer, Ph.D., from the University of Glasgow, UK, and colleagues point out that epidemiological studies have shown that there is a correlation between pre-eclampsia in pregnant women and the increased risk of subsequent CHD; however, there is not enough data to conclude this conclusion To explain the mechanism of this correlation. Forty women from the first trimester with a history of proteinuria and preeclampsia between 1975 and 1985 were included in the study, which matched 40 women with gestational age, smoking, and current body mass index