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蕈样肉芽肿(mycosis fungoides,MF)是原发性皮肤T细胞淋巴瘤中最常见的一种类型,低度恶性,在病程早期可有红斑、丘疹、苔藓化、皮肤异色等多种皮肤损害,缺乏特异性,易误诊及漏诊。近年来出现的多种辅助检查手段如免疫组化、基因重排、流式细胞术、皮肤镜等成为提高MF早期诊断率的有效工具。我科联合应用多种辅助检查手段,诊断病程仅6个月的早期蕈样肉芽肿1例,现报告如下。
Mycosis fungoides (MF) is the most common type of primary cutaneous T-cell lymphoma, with low grade malignancy. It may have various types of skin such as erythema, papules, mossy skin, Damage, lack of specificity, misdiagnosis and missed diagnosis. In recent years, a variety of auxiliary examination methods such as immunohistochemistry, gene rearrangement, flow cytometry, dermoscopy and other tools to improve the early diagnosis of MF an effective tool. Our department jointly applied a variety of auxiliary examinations, the diagnosis of disease duration of only 6 months early mycosis fungoides in 1 case, are as follows.