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对72例肺癌患者的血液流变学(下称血流变)检测,以50例健康人作对照,结果表明肺癌患者存在高粘血症。对其中37例患者除常规治疗外加用卡介苗多糖核酸(BCG—PSN)治疗(试验组),另35例仅作常规治疗(对照组)。观测两组治疗后血流变学变化。结果表明:试验组血流变有明显改善,其中μb、μg、Fig、HCT等指标下降,与健康组相比无明显差异(P>0.05)。而对照组无明显变化。以上提示卡介苗多糖核酸对肺癌高粘滞血症的治疗有积极意义,可作为肺癌的一种辅助治疗手段。
The blood rheology of 72 patients with lung cancer (hereinafter referred to as hemorheology) was tested and compared with 50 healthy subjects. The results showed that patients with lung cancer had hyperviscosity. Of these, 37 patients were treated with BCG-PSN (experimental group) in addition to routine treatment, and the other 35 were treated only with conventional therapy (control group). Observed changes in blood rheology after treatment in both groups. The results showed that the blood flow of the experimental group was significantly improved, including μb, μg, Fig, HCT, and other indicators. There was no significant difference compared with the healthy group (P>0.05). There was no significant change in the control group. The above suggests that BCG polysaccharide nucleic acid has positive significance for the treatment of hyperviscosity in lung cancer, and can be used as an adjuvant therapy for lung cancer.