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目的探讨螺旋CT增强双期扫描技术在评价肺癌非手术治疗疗效中的作用。资料与方法52例经非手术治疗肺癌患者行螺旋CT增强双期扫描(以4ml/s的流率注入对比剂,分别在25s及90s行胸部螺旋扫描),记录肺癌增强前后各时相的CT值并计算强化净增值,并与文献结果对照。记录25s及90s时肺癌的强化模式。结果治疗后肺癌平扫CT值、增强后25s及90sCT值分别为(42.20±7.43)HU、(57.35±10.09)HU、(71.85±12.45)HU。平扫CT值与文献报道的未经治疗的肺癌平扫CT值(40.70HU)差异无统计学意义(t=1.455,P=0.152(0.05)。强化净增值(29.46±10.85)HU明显低于文献报道的未经治疗肺癌的强化净增值(35.79HU)(t=4.206,P=0.001<0.05)。52例中32例90s时表现为均匀强化;32例中25s时21例表现为混杂强化,7例表现为均匀强化,2例表现为中央强化,2例表现为周边强化。结论治疗后肺癌有逐渐强化的趋势;肺癌强化净增值能反映肺癌的血供,可作为肺癌非手术治疗疗效评价指标之一。
Objective To investigate the role of enhanced spiral CT double-phase scanning in the evaluation of non-surgical treatment of lung cancer. Materials and Methods 52 cases of non-surgical treatment of lung cancer patients with double-phase spiral CT enhanced scanning (4ml / s flow rate injection of contrast agent, respectively, 25s and 90s line of chest spiral scan), recorded before and after lung cancer enhanced CT Value and calculate enhanced net added value, and with the literature results. Record 25s and 90s enhanced model of lung cancer. Results After the treatment, the value of CT scan of lung cancer was (42.20 ± 7.43) HU, (57.35 ± 10.09) HU and (71.85 ± 12.45) HU respectively at 25s and 90sCT. There was no significant difference between plain CT value and untreated lung cancer CT value (40.70HU) reported in the literature (t = 1.455, P = 0.152 (0.05), and the net enhancement value (29.46 ± 10.85) HU was significantly lower than The net increase of untreated lung cancer (35.79HU) was reported in the literature (t = 4.206, P = 0.001 <0.05) .32 of 32 cases showed uniform enhancement at 90s and 21 cases showed mixed enhancement at 25s , 7 cases showed uniform enhancement, 2 cases showed central enhancement, and 2 cases showed peripheral enhancement.Conclusions The lung cancer has a tendency of strengthening gradually after treatment.Enhanced net value of lung cancer can reflect the blood supply of lung cancer and can be used as non-surgical treatment of lung cancer One of the evaluation indicators.