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应用免疫组化方法对60例尖锐湿疣病人组织中人乳头瘤病毒(HPV)感染状况进行组织切片和细胞涂片检测。结果显示70%的组织切片和10%细胞涂片中可见到HPV阳性细胞。阳性细胞主要见于具有诊断特征的空泡细胞中,细胞空泡程度越明显其阳性程度越强。表明空泡细胞是HPV感染后上皮细胞出现的形态学改变。含有成熟的病毒颗粒。组织切片中HPV检出率明显高于细胞涂片。在不同性别和不同年龄的患者中HPV的检出率无明显差异。
Immunohistochemistry was used to detect the tissue infection and cell smears of human papillomavirus (HPV) in 60 cases of condyloma acuminatum. The results showed that HPV-positive cells were found in 70% of tissue sections and 10% of cell smears. Positive cells are mainly found in the vacuolar cells with diagnostic characteristics, the more the degree of cell vacuolization the more positive the degree. It showed that vacuolar cells were the morphological changes of epithelial cells after HPV infection. Contains mature virus particles. The detection rate of HPV in tissue sections was significantly higher than that in cell smears. There was no significant difference in the detection rate of HPV among patients of different genders and ages.