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Objective: To investigate the chemical constituents of Polygala japonica Houtt. . Methods: The constituents were separated and purified by column chromatographies with silical gel, RP-silical gel and Sephadex LH-20. Their structures were elucidated on the basis of spectral data (IR, MS, 1H-NMR, 13 C-NMR, HMQC and HMBC). Results: Totally 15 compounds were obtained from Polygala japonica Houtt. and their structures were identified as castaprenol-12 ( I ),β-sitosterol ( II ), stigmasterol ( I ), stigmasta-7, 22-di-ene-3-one (IV ), n-dotriacontanol (V ), n-hexadecanol (VI), arachidic acid ( VI ), ero-gosterol ( VIIII ), kaempferol ( IX ), quercetin ( X ), daucosterol ( XI ), p-hydroxybenzoic acid ( XI ), coumaric acid ( XIII ), rhamnocitrin 3-O-β-D-galactopyranoside ( XIV ), quercetin 3-O-β-D-glucopyranoside ( XV ). Conclusion: Compounds I , I , IV , V , VI , VII , VIII, XII , XIII and XIV were obtained from this plant for the first time.
Objective: To investigate the chemical constituents of Polygala japonica Houtt. . Methods: The constituents were separated and purified by column chromatographies with silical gel, RP-silical gel and Sephadex LH-20. Their structures were elucidated on the basis of spectral data (IR , MS, 1H-NMR, 13 C-NMR, HMQC and HMBC). Results: Totally 15 compounds were obtained from Polygala japonica Houtt. and their structures were identified as castaprenol-12 (I ), β-sitosterol (II ), stigmasterol (I ), stigmasta-7, 22-di-ene-3-one (IV ), n-dotriacontanol (V ), n-hexadecanol (VI), arachidic acid ( VI ), ero-gosterol (VIIII ), kaempferol ( IX), quercetin (X ), daucosterol (XI ), p-hydroxybenzoic acid (XI ), coumaric acid (XIII ), rhamnocitrin 3-O-β-D-galactopyranoside (XIV ), quercetin 3-O-β-D- Glucopyranoside (XV). Conclusion: Compounds I, I, IV, V, VI, VII, VIII, XII, XIII and XIV were obtained from this plant for the first time.