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运用益气健脾法加激素治疗原发性肾病综合征（PNS）合并心电图异常47例，并以单纯激素治疗26例作对照。结果：2组对PNS疗效无显著差异（P＞0．05）。而治疗组激素不良反应的发生率（14．9％）明显地低于对照组（42．3％）（P＜0．01）。对合并心电图异常的疗效，治疗组心电图恢复率（80．85％）明显地优于对照组（53．85％）（P＜0．01）。表明益气健脾法可提高心肌细胞能量代谢、蛋白质代谢及增强酶的活性，从而改善全身蛋白质──能量代谢，是使其心电图异常得以恢复的关键，同时减轻使用激素所产生的不良反应。
Forty-seven patients with primary nephrotic syndrome (PNS) and electrocardiogram (ECG) were treated with supplementing qi and spleen plus hormones, and 26 patients treated with hormone alone were used as controls. Results: There was no significant difference in the efficacy of PNS between the two groups (P> 0.05). The incidence of adverse reactions in the treatment group (14.9%) was significantly lower than that in the control group (42.3%) (P <0.01). The effect of electrocardiogram anomaly on the ECG in the treatment group was significantly better than that in the control group (80.85% vs 53.85%, P <0.01). It shows that the method of invigorating the spleen and invigorating the spleen can improve energy metabolism, protein metabolism and enzyme activity of cardiomyocytes, thus improving the whole body protein ─ ─ energy metabolism, which is the key to recover the abnormal ECG and reduce the adverse reactions caused by the use of hormones.