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目的观察α-硫辛酸与甲钴铵联合治疗糖尿病周围神经病变的疗效。方法 80例糖尿病周围神经病变患者随机分为对照组和治疗组,对照组40例,单用甲钴铵,连用4周;治疗组40例,在对照组基础上,加用α-硫辛酸连用4周。结果治疗组有效率95%,明显高于对照组76%(P<0.05),神经传导速度明显改善。结论α-硫辛酸与甲钴铵联合应用可明显提高糖尿病周围神经病变的治疗效果。
Objective To observe the therapeutic effect of α-lipoic acid and mecobalamin in the treatment of diabetic peripheral neuropathy. Methods 80 patients with diabetic peripheral neuropathy were randomly divided into control group and treatment group, control group 40 cases, monotherapy with cobaltous ammonium for 4 weeks; the treatment group 40 cases, on the basis of the control group, plus α-lipoic acid used 4 weeks. Results The effective rate of the treatment group was 95%, which was significantly higher than that of the control group (P <0.05), and the nerve conduction velocity was significantly improved. Conclusions The combination of α-lipoic acid and methylcobalamin can obviously improve the therapeutic effect of diabetic peripheral neuropathy.