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目的探讨围产因素对新生儿ABO溶血病的影响。方法已证实ABO溶血病患儿按平产分娩及围产因素(包括剖宫产,胎儿宫内窘迫、羊水污染、羊水少)分娩,分Ⅰ组及Ⅱ组,所有患儿入院前采取静脉血,通过BS-400全自动生化分析仪测黄疸指数、血清总胆红素(TB)、直接胆红素(DB)进行比较。结果两组指标TB、DB采用HellingT2多元系统分析法,取Holelling-lawley Tvace统计量,所得P值=0.0287(P(0.05),说明Ⅰ组Ⅱ组两指标TB、DB的总体均值不同,两组有统计学意义。结论围产多种因素对新生儿ABO溶血病影响密切,需早期诊断,早期干预,动态观察黄疸指数,尽可能降低胆红素指数,使之处于一个较低水平,对于新生儿平稳渡过前7天高危期,降低神经系统后遗症起到了积极的作用。
Objective To investigate the effect of perinatal factors on neonatal ABO hemolytic disease. Methods Confirmed that children with ABO hemolytic disease were delivered by labor and perinatal factors (including cesarean section, fetal distress, amniotic fluid contamination, oligohydramnios) .It was divided into group I and group II, and all children received venous blood before admission The bilirubin index, serum total bilirubin (TB) and direct bilirubin (DB) were compared by BS-400 automatic biochemical analyzer. Results The two groups of indicators TB, DB using HellingT2 multiple system analysis, take the Holelling-lawley Tvace statistics, the value of P = 0.0287 (P (0.05), indicating that Ⅰ group Ⅱ group two indicators of TB, DB overall mean difference between the two groups There are statistical significance.Conclusion The multiple factors of perinaton have a close impact on neonatal ABO hemolytic disease.It needs early diagnosis and early intervention.It can observe the jaundice index dynamically and reduce the bilirubin index as low as possible.It is a new level Stably through the first seven days of high-risk children, reduce the nervous system sequelae played a positive role.