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内皮素（ｅｎｄｏｔｈｅｌｉｎ，ＥＴ）是血管内皮细胞分泌的具有极强缩血管活性的多肽类物质。已在动物实验和心、脑梗塞等病人中发现，缺血后再灌注可导致血浆ＥＴ－１含量异常升高，其程度与梗塞面积密切相关，而ＥＴ－１拮抗剂则对缺血后再灌注组织有保护作用。临床研...
Endothelin (ET) is a highly vasoactive peptide that is secreted by vascular endothelial cells. It has been found in animal experiments and patients with heart and cerebral infarction that reperfusion after ischemia can lead to abnormally elevated plasma ET-1 levels, which is closely related to the infarct size, whereas ET-1 antagonists are Perfusion tissue has a protective effect. Clinical research...