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目的探讨急性高眼压状态与房水中心房利钠居肽含量的关系。方法应用放射免疫分析法检测急性高眼压状态家兔中的心房利钠尿肽水平，并进行统计学处理。结果放射免疫法检测，高眼压组与对照组房水中的心房利钠尿肽水平分别为118．0±21pg／ml，70．2±18．6pg／ml，5．0±1．8pg／ml（P＜0．05）。结论高眼压时房水中的心房利钠原肽水平明显升高，且与眼压呈正相关。
Objective To investigate the relationship between acute intraocular hypertension and atrial natriuretic peptide content in aqueous humor. Methods Radioimmunoassay was used to detect the level of atrial natriuretic peptide in rabbits with acute ocular hypertension. The levels of atrial natriuretic peptide were measured and statistically analyzed. Results Radioimmunoassay showed that the levels of atrial natriuretic peptide in aqueous humor of ocular hypertension and control groups were 118.0 ± 21pg / ml, 70.2 ± 18.6pg / ml and 5.0 ± 1.8pg / ml (P <0.05). Conclusions Intraocular natriuretic peptide levels in aqueous humor were significantly elevated in patients with intraocular hypertension and were positively correlated with intraocular pressure.