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血管的形成有两条途径:血管发生(vasculo—genesis)和血管生成(angiogenesis)。血管发生指胚胎发育过程中原始血管网的形成过程;而血管生成是指已存在的毛细血管网重新塑型的生理及病理状态。血管生成在胚胎发育、排卵、损伤修复、糖尿病性视网膜炎和类风湿性关节炎以及恶性肿瘤的发生和发展等许多生理和病理状态下起着十分重要的作用。恶性淋巴瘤(malignant lymphoma)是原发于淋巴结和淋巴结外淋巴组织的恶性肿瘤,是儿童最常见的恶性肿瘤之一。近年来血管生成在淋巴瘤的发生、
There are two ways for the formation of blood vessels: vasculo-genesis and angiogenesis. Angiogenesis refers to the process by which the original blood vessel network develops during embryonic development; whereas angiogenesis refers to the physiological and pathological state of an existing capillary network remodeling. Angiogenesis plays a very important role in many physiological and pathological states, such as embryonic development, ovulation, injury repair, diabetic retinitis and rheumatoid arthritis, and the development and progression of malignant tumors. Malignant lymphoma (malignant lymphoma) is a malignant tumor originating in lymph nodes and extranodal lymph node tissue, is one of the most common malignant tumors in children. Angiogenesis in recent years, the incidence of lymphoma,