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目的:分析临床药师参与儿童哮喘性疾病治疗的疗效,探讨临床药学服务的可行性。方法:选取2010年10月—2013年10月间诊治的50例哮喘患儿,将其分为干预组(n=25)和非干预组(n=25),干预组患儿临床药师参与患者治疗的全过程,并协助临床医生制订个体化治疗方案,规范药物治疗,患儿出院后药师继续指导用药;非干预组患儿在治疗全过程及出院后指导用药均无临床药师参与,两组均进行依从性调查分析,对比两组患儿的临床疗效。结果:干预组患儿治疗的总有效率、住院天数、发作频率和药物不良反应的发生率均显著优于非干预组(P<0.01),治疗依从性良好率也优于非干预组(P<0.05)。结论:临床药学干预儿童哮喘性疾病的治疗提高了患儿用药依从性和药物治疗效果,减少了药物不良反应的发生,使药物治疗更为安全、有效,同时丰富了临床药师自身知识结构,值得推广。
Objective: To analyze the efficacy of clinical pharmacists in the treatment of children with asthma and explore the feasibility of clinical pharmacy services. Methods: Fifty children with asthma who were diagnosed and treated between October 2010 and October 2013 were divided into intervention group (n = 25) and non-intervention group (n = 25). Clinical pharmacists participated in the intervention group The whole process of treatment, and to help clinicians to develop individualized treatment programs, regulate drug treatment, pediatric patients continue to guide the medication after discharge; non-intervention group of children in the whole course of treatment and after discharge from the hospital without the guidance of pharmacists, two groups All were conducted compliance analysis, compared the clinical efficacy of two groups of children. Results: The total effective rate, days of hospitalization, frequency of seizure and adverse drug reactions were significantly better in intervention group than in non-intervention group (P <0.01), and the rate of good compliance was also better than that of non-intervention group <0.05). Conclusion: The intervention of clinical pharmacy in children with asthma can improve the drug compliance and drug treatment in children, reduce the incidence of adverse drug reactions, make the drug treatment more safe and effective, and enrich the knowledge structure of clinical pharmacists, which is worthwhile Promotion.