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正常人体是由细胞的增殖、分化和凋亡共同调节的 ,白血病是异常克隆过度增殖 ,凋亡受抑引起。研究表明 ,肿瘤坏死因子 (ＴＮＦ)α是造血系统调控因子 ,对白血病细胞有生长抑制和促进增殖作用。可溶性ＴＮＦ受体Ⅰ (ｓＴＮＦＲⅠ )与ＴＮＦα特异性结合后调节ＴＮＦα的生物学活
Normal human body is a combination of cell proliferation, differentiation and apoptosis co-regulation, leukemia is abnormal clonal hyperproliferation, inhibition caused by depression. Studies have shown that tumor necrosis factor (TNF) alpha is a hematopoietic system regulatory factor that inhibits the growth of leukemic cells and promotes proliferation. Soluble TNF receptor I (sTNFRI) binds specifically to TNFα to regulate the biological activity of TNFα