论文部分内容阅读
[病例]女,45y,体重52kg.因胸闷、心悸、夜间阵发性呼吸困难,双下肢浮肿,行多普勒超声心动图:示心包积液,肺部CT提示右下叶背段占位,考虑为肺Ca可能伴血行转移、心包转移.经肺穿刺病理诊断证实为肺原发性腺癌.经DDP、VDS等化疗,症状有所控制,但化疗2mo后胸闷、心悸、呼吸困难加重,再次入院治疗.入院后经抽胸水,胸腔内VP_(16)100mg+VCR 1mg+利多卡因2ml注入,并用头孢噻肟抗感染及对症处理等,症状控制后给予紫杉醇(paclitaxel安素泰,澳大利亚Faulding公司,批号8026857X)化疗化疗前12h及6h分别给予地塞米松10mg,po,化疗前30min给予苯海拉明50mg,po及西米替丁300mg,iv.紫杉醇180mg溶于5%GS注射液500ml中,用玻璃瓶及有滤网的输血胶管,滴注前经心电监测显示:HR120 beats/min,心律
[Case] female, 45y, weight 52kg. Due to chest tightness, heart palpitations, nocturnal paroxysmal dyspnea, both lower extremity edema, line Doppler echocardiography: showed pericardial effusion, , Consider the possible metastasis of the lung Ca with blood, pericardial metastasis.Pathological diagnosis of pulmonary primary pulmonary adenocarcinoma confirmed by DDP, VDS and other chemotherapy, the symptoms are controlled, but 2 months after chemotherapy chest tightness, palpitations, dyspnea increased, And then admitted to hospital for treatment.After admission, the patients were injected with paclitaxel (VP) (16) 100mg + VCR 1mg + lidocaine in the chest cavity and anti-infection and symptomatic treatment with cefotaxime. Company, lot number 8026857X) 12h and 6h before chemotherapy were given dexamethasone 10mg, po, 30min before chemotherapy given diphenhydramine 50mg, po and cimetidine 300mg, iv. Paclitaxel 180mg dissolved in 5% GS injection 500ml , With a glass bottle and filter blood transfusion tube, ECG monitoring before instillation showed: HR120 beats / min, heart rate