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目的 探讨 2 4h动态血压监测 (2 4hABPM )的收缩压 (SBP)、舒张压 (DBP)及脉压 (PP)与心脑肾靶器官损害 (TOD)的关系。方法 采用无创性携带式动态血压监测仪对 15 8例高血压病病人进行2 4hABPM ,按平均压 (MBP)≤ 115mmHg和 >115mmHg分为两组 ;再以PP≤ 6 0mmHg、6 1～ 80mmHg和≥81mmHg分为 3个亚组。结果 随PP增加 ,TOD逐步增加 (P <0 0 1) ;PP相同而MBP不同的两组TOD无差异 (P >0 0 5 ) ,但MPB >115mmHg组的SBP、DBP和MBP均高于MBP≤ 115mmHg者 (P <0 0 1)。 结论 高血压病病人的PP比SBP、DBP与TOD的关系更密切
Objective To investigate the relationship between systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse pressure (PP) and target organ damage of heart and brain and kidney (TOD) in 24 h ambulatory blood pressure monitoring (24 hABPM) Methods Fifteen 15 hypertensive patients underwent 24 h ABPM by means of a noninvasive portable ambulatory blood pressure monitor. The patients were divided into two groups according to mean pressure (MBP) ≤ 115 mmHg and> 115 mmHg. Then PP 60 mmHg, 61-80 mmHg, ≥ 81mmHg is divided into 3 subgroups. The results showed that the TOD was increased with the increase of PP (P <0.01). There was no difference in TOD between the two groups with the same PP and MBP (P> 0.05), but the SBP, DBP and MBP of MPB> 115mmHg group were higher than that of MBP ≤ 115 mmHg (P <0 0 1). Conclusions PP in patients with hypertension is more closely related to SBP, DBP and TOD