【摘 要】
：
Boehringer Ingelheim(BI)公司与Priaxon公司最近签约,将斥巨资(约8600万欧元)联手开发若干用于治疗癌症的mdm2/p53抑制剂。p53为调控细胞周期所必需的一种人肿瘤抑制蛋白。
论文部分内容阅读
Boehringer Ingelheim(BI)公司与Priaxon公司最近签约,将斥巨资(约8600万欧元)联手开发若干用于治疗癌症的mdm2/p53抑制剂。p53为调控细胞周期所必需的一种人肿瘤抑制蛋白。在约50%的人类肿瘤组织中,p53功能缺失,这可能是因其基因突变和(或)因p53的负调节因子mdm2(鼠双微体2)基
Boehringer Ingelheim (BI) and Priaxon recently signed a contract to invest heavily (about 86 million euros) in the development of several mdm2 / p53 inhibitors for the treatment of cancer. p53 is a human tumor suppressor protein necessary for the regulation of the cell cycle. In about 50% of human tumor tissues, p53 function is absent, possibly due to its genetic mutation and / or the negative regulator of p53, mdm2 (murine diabody 2)
其他文献
本刊讯一个电子废物处理和回收中心9月将在天津市动工兴建,并将于明年正式投入使用。该中心将成为我国华北地区的电子垃圾处理回收基地,每年将综合利用电子废物3万吨。项目建
Acta Pharmaceutica Sinica B(APSB)has been accepted for inclusion in Pub Med Central(PMC),the world’s largest and most-used biomedical literature database.Curre
China’s two most powerful organizations,the National People’s Congress and the National Committee of the Chinese People’s Po-litical Consultative Conference
A gneissic granite with an U-Pb age of 313±4 Ma was found in northeastern Fujian Province,South China.It is an S-type granite characterized by high K2O,Al2O3 a
对于新形式下的医药营销来说,如果说“变”是传播需要具备的对大局、细节把握以及取舍的智慧和勇气,那么“恒”就是决定传播长远收益的明悟和执着。
For the new forms of m
EORTC 10994/BIG 00-01研究小组曾在体外试验中观察到,基因标志物能够预测常规化疗药物对细胞的生长抑制及毒性效应;随后,该小组检测了新辅助化疗Ⅲ期临床试验中雌激素受体阴
婚丧嫁娶,家计大事。一个人的一生,这类事往往只有一回。把事情办得体面风光,而又无害世道人心,别人无权置喙。但是,被云南昭通永善县称之为当地“史上最牛”的嫁女事件,却
时至今日,对搬迁决策的酝酿过程与具体考虑,仍没有权威的说法,“你们要能代表老百姓的利益,我们给你提供信息,不代表老百姓的利益就对不起。”陇南市
Up to now, there is s
请下载后查看，本文暂不支持在线获取查看简介。
Please download to view, this article does not support online access to view profile.