论文部分内容阅读
矽肺至今仍是一种常见的职业病,为了弄清它的病理过程曾进行过许多实验研究,但是肺组织中细胞种类较多,应用光学显微镜观察甚至难以区分脱落的Ⅱ型肺泡上皮细胞和游离的肺泡巨噬细胞,因此电镜观察乃是研究肺组织对异物反应的重要手段。由于矽肺组织中含有坚硬的石英尘,不易得到理想的超薄切片,致使电镜观察受到限制,有关矽肺超微结构变化的报告较少。Miller等(1978)观察到大鼠吸入石英尘半年
Silicosis is still a common occupational disease so far. In order to find out its pathological process, many experimental studies have been conducted. However, there are many types of cells in the lung tissue. It is even difficult to distinguish the exfoliated type II alveolar epithelial cells from the free type by light microscopy Alveolar macrophages, so electron microscopy is to study lung tissue on the foreign body an important means of response. Due to the presence of hard quartz dust in the silicosis tissue, it is not easy to obtain ideal ultrathin sections, which limits the observation of electron microscopy. There are few reports on the ultrastructural changes of silicosis. Miller et al. (1978) observed that rats inhaled quartz dust for six months