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目的探讨天花粉蛋白联合米非司酮治疗持续性宫外孕的疗效。方法对于16例确诊持续性宫外孕的患者,给予天花粉蛋白2.4mg单次肌内注射,同时给予地塞米松10mg肌内注射抗过敏。给予米非司酮每日100mg口服,共5d,复查血β-HCG,B超,血常规,每3～5日一次,严密监测血压,腹痛及阴道出血情况。结果 16例患者血β-HCG均下降至正常,无l例行二次手术。结论天花粉蛋白是持续性宫外孕理想可靠的治疗方法。
Objective To investigate the efficacy of trichosanthin combined with mifepristone in the treatment of persistent ectopic pregnancy. Methods Twenty-six patients with persistent ectopic pregnancy were given a single intramuscular injection of trichosanthin (2.4 mg) and an intramuscular injection of 10 mg dexamethasone for anti-allergy. Given mifepristone 100mg daily oral, a total of 5d, review of blood β-HCG, B ultrasound, blood routine, once every 3 to 5 days, close monitoring of blood pressure, abdominal pain and vaginal bleeding. Results The blood β-HCG levels of 16 patients decreased to normal without l routine second surgery. Conclusion Trichosanthin is an ideal and reliable treatment for persistent ectopic pregnancy.