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流行病学研究发现中度贫血与不良的产期后果有关。亦发现母亲高血红蛋白与不良妊娠后果危险增加有关联 ,但未证明这种关联是因果性的。将这种关联归因于妊娠高血压病征和先兆子痫更好。妊娠期的这些并发症的病理生理机理能引起较高的血红蛋白浓度和胎儿应激。因此 ,血红蛋白浓度高于正常应看作是可能的妊娠并发症的指征 ,未必是铁营养充足的征兆 ,因为补铁并不使血红蛋白增加至高于氧传送所需的最适浓度。
Epidemiological studies have found that moderate anemia is associated with poor outcome. Her mother’s high hemoglobin was also found to be associated with an increased risk of adverse pregnancy outcomes, but this association was not proven to be causal. Attributed this association to symptoms of pregnancy-induced hypertension and preeclampsia. The pathophysiology of these complications during pregnancy leads to higher hemoglobin concentrations and fetal stress. Therefore, a higher than normal hemoglobin level should be considered an indication of possible pregnancy complications and not necessarily a sign of adequate iron nutrition, as iron supplementation does not increase hemoglobin above the optimal concentration required for oxygen delivery.