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目的探讨重组人P53腺病毒注射液结合介入治疗妇科盆腔恶性肿瘤的新方法。方法对28例妇科中晚期恶性肿瘤患者经导管动脉内灌注重组人P53腺病毒注射液。结果 28例36次插管全部成功,顺利进行药物灌注及栓塞,治疗后患者生存生活质量提高,症状减轻,生存期延长。结论 rAd-p53结合介入治疗中晚期妇科盆腔恶性肿瘤,具有较高的推广应用价值。
Objective To explore a new method of recombinant human P53 adenovirus injection combined with interventional treatment of gynecologic pelvic malignancies. Methods 28 cases of advanced gynecological malignant tumors were transcatheter arterial infusion of recombinant human P53 adenovirus injection. Results All the 36 cases of intubation were successful in 28 cases, and drug infusion and embolization were successfully carried out. After treatment, the quality of life and the quality of life were improved, the symptoms were relieved, and the survival period was prolonged. Conclusion rAd-p53 combined with interventional treatment of advanced gynecologic pelvic malignancies, has a high value of popularization and application.