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用蘿芙木屬(Rauwolfia)植物的生物鹼来治疗高血压已受到普遍的重视;其中以Reserpine最受注意,它有降低血压作用,并有特殊的鎮靜效能。我国广东、广西、云南諸省出产蘿芙木植物均为Rauwolfia verticillata(Lour.)Baill.,它的化学和藥理均有报导。临床正拟試用国产蘿芙木治疗高血压。刘鑄晋等用离子交换剂获得蘿芙木全鹼,本文是研究它的毒性、降压及中樞鎮靜作用,以便推荐它到临床試用。
The treatment of hypertension with alkaloids from the Rauwolfia plant has gained widespread attention; among them, Reserpine is most notably the one that has a hypotensive effect and has a special sedative effect. Rauwolfia verticillata (Lour.) Baill., Produced in China’s Guangdong, Guangxi and Yunnan provinces, is both chemically and pharmacologically reported. Clinical trial is intended to test the domestic rofu wood treatment of hypertension. Liuzhuo Jin and other ion exchangers to obtain Rauvall alkali, this article is to study its toxicity, antihypertensive and central sedation in order to recommend it to clinical trials.