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[目的]探讨胸部良性疾病单孔胸腔镜手术后应用负压引流球胸腔引流的临床研究.[方法]选取2014年5月至2017年5月在本院胸外科行胸腔镜手术治疗患者的182例作为研究对象.根据患者接受的胸腔镜术式不同将患者分为单孔胸腔镜手术且术后应用负压引流球胸腔引流组(以下简称单孔腔镜组)102例和传统胸腔镜手术术后应用普通引流管组(以下简称传统腔镜组)80例.单孔腔镜组患者接受单孔胸腔镜手术,传统腔镜组接受三孔胸腔镜手术.比较两组患者的术中出血量、手术时间、住院时间、引流量、术后疼痛、术后并发症等指标,3个月后评价生活质量.[结果]单孔腔镜组患者的术中出血量、引流量少于传统腔镜组,住院时间短于传统腔镜组,但手术时间长于传统腔镜组,差异均具有统计学意义(P<0.05);单孔腔镜组患者术后3d疼痛最大值、术后7d疼痛最大值、术后7d疼痛最小值均低于传统腔镜组,差异均具有统计学意义(P0.05);3个月后,单孔腔镜组患者的生理机能评分、生理职能评分、躯体疼痛评分、社会功能评分、情感职能评分以及精神健康评分均高于传统腔镜组,差异具有统计学意义(P<0.05).[结论]与传统的胸腔镜术后应用普通引流管相比,单孔胸腔镜术后应用负压引流球胸腔引流治疗胸外科疾病可以有效的减少术中出血量、缩短住院时间、减少引流量、缓解疼痛感,提升患者短期的生活质量,值得临床推广.“,”[Objective]To explore the clinical application of single-hole thoracoscopic surgery and negative pressure drainage after surgery for benign chest diseases.[Methods]A total of 182 patients who underwent thoracoscopic surgery in our hospital from May 2014 to May 2017 were enrolled in this study.According to the different thoracoscopic procedures,patients were divided into the single-hole thoracoscopic surgery and postop-erative application of negative pressure drainage ball drainage group (hereinafter referred to as single-hole tho-racoscopic surgery group)with 102 cases and the conventional thoracoscopic surgery and postoperative applica-tion of ordinary drainage group (hereinafter referred to as traditional thoracoscopic surgery group)with 80 ca-ses.Patients in the single-hole thoracoscopic surgery group underwent single-hole thoracoscopic surgery,while patients in the traditional thoracoscopic surgery group received three-hole thoracoscopic surgery.The intraop-erative blood loss,operation time,length of hospitalization and drainage were compared between the two groups.Postoperative pain,postoperative complications,and quality of life for 3 months after surgery were e-valuated as well.[Results]The intraoperative blood loss and drainage volume of patients with the single hole thoracoscopic surgery were less than those of the traditional thoracoscopic surgery group (P <0.05),but the operation time in the single-thoracic surgery group was longer than that of the conventional thoracoscopic sur-gery group (P <0.05).The hospitalization time of patients with single-hole thoracoscopic surgery was shorter than that in the conventional thoracoscopic surgery group;the difference was statistically significant (P <0.05).The maximum pain at 3 and 7 days postoperatively,and the lowest pain at 7 days after operation in the single-hole thoracoscopic surgery group were lower than those in the conventional thoracoscopic surgery group;the differences were statistically significant(P <0.05).However,there was no statistically significant difference in the incidence of postoperative complications between the two groups.After 3 months of surgery,the scores of physiological function,physical pain,social function,emotional function and mental health in pa-tients who underwent single-hole thoracoscopic surgery were significantly higher than those in patients under-went traditional thoracoscopic surgery;the differences were statistically significant (P <0.05).[Conclusion]Compared to traditional thoracoscopic surgery with ordinary drainage tube,the use of single-hole thoracoscopic surgery with negative pressure thoracic drainage treatment of thoracic surgery can more effectively reduce the amount of intraoperative blood loss,shorten the length of hospital stay,reduce drainage volume,relieve pain, and improve the quality of life.It is worthy of clinical promotion.