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目的:探讨苯磺酸氨氯地平治疗高血压的临床治疗效果及可行性。方法:选择我院收治的68例轻、中度高血压患者,相应给予苯磺酸氨氯地平5～10mg/d,观察疗程8周,采取自身对照的方式,观察不同患者服用苯磺酸氨氯地平后相应的血压、生化指标变化及不良反应。结果:治疗8周后患者收缩压、舒张压与治疗前相比有明显降低,对比差异有统计学意义(P<0.05)。其中显著进步48例(71.05%),有效14例(20.12%),总有效率达90.18%,出现不良反应仅7.39%。结论:苯磺酸氨氯地平治疗轻、中度高血压安全、有效,且不良反应低,是治疗轻中度高血压的理想药物,值得临床推广使用。
Objective: To investigate the clinical efficacy and feasibility of amlodipine besylate in the treatment of hypertension. Methods: A total of 68 patients with mild to moderate hypertension admitted to our hospital were enrolled in this study. Amlodipine besylate (5 ~ 10 mg / d) was given for 8 weeks. A self-control study was conducted to observe the effect of different doses of ammonia The corresponding blood pressure after chlorpheniramine, biochemical changes and adverse reactions. Results: After 8 weeks of treatment, the systolic blood pressure and diastolic blood pressure of patients were significantly lower than those before treatment, the difference was statistically significant (P <0.05). Significant improvement in 48 cases (71.05%), effective in 14 cases (20.12%), the total effective rate was 90.18%, the adverse reaction was only 7.39%. Conclusion: Amlodipine besylate is safe and effective in treating mild and moderate hypertension with low adverse reactions. It is an ideal medicine for treating mild to moderate hypertension and is worthy of clinical promotion.