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雌激素主要通过雌激素受体(ER)的介导发挥生物学效应。大量研究发现,雌激素受体在基底前脑、间脑、中脑、海马、杏仁体、大脑皮质、小脑皮质等均有广泛分布,且具有性别差异。除神经元外,神经胶质细胞也存在雌激素的受体,其可能参与了雌激素对认知、情绪、内分泌、神经营养、生殖、肿瘤发生等多种神经功能的调节。雌激素对神经细胞的作
Estrogen exerts its biological effects primarily through the mediation of the estrogen receptor (ER). A large number of studies have found that estrogen receptors in the basal forebrain, diencephalon, midbrain, hippocampus, amygdala, cerebral cortex, cerebellar cortex are widely distributed, and have gender differences. In addition to neurons, glial cells also exist estrogen receptors, which may be involved in the regulation of estrogen on a variety of neurological functions such as cognition, emotion, endocrine, neurotrophic, reproductive, tumorigenesis. Estrogen for nerve cells