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目的探讨早发型重度子痫前期治疗、终止妊娠时机与母儿的结局。方法回顾性分析64例不同孕周早发型重度子痫前期患者的临床资料。根据其发病孕周分成3组,即A组(孕周<28周)10例、B组(28周≤孕周<32周)30例、C组(32周≤孕周<34周)24例。结果 A、B、C 3组孕产妇并发症发生率分别为70.0%,66.7%,20.8%,3组孕产妇并发症发生率比较,差异有统计学意义(P<0.05);保守治疗时间B组明显长于其他两组(P<0.05);B、C两组分娩方式以剖宫产为主。结论早发型重度子痫前期病情重,并发症发生率高,围生儿预后差,在期待治疗过程中应严密监护母体胎儿情况,适当延长孕周,适时终止妊娠,提高新生儿存活率。
Objective To explore the treatment of early-onset severe preeclampsia, the timing of termination of pregnancy and maternal and child outcomes. Methods The clinical data of 64 patients with early-onset severe preeclampsia were retrospectively analyzed. According to their gestational age, they were divided into 3 groups: group A (gestational age <28 weeks), group B (28 weeks ≤ gestational weeks <32 weeks), group C (32 weeks ≤ gestational weeks <34 weeks) example. Results The incidence of maternal complications in groups A, B and C were 70.0%, 66.7% and 20.8%, respectively. The incidence of maternal complications in the three groups was statistically significant (P <0.05). The conservative treatment time B Group was significantly longer than the other two groups (P <0.05); B, C two groups delivery mode to cesarean section. Conclusions Premature onset severe preeclampsia is characterized by severe illness and high complication rate. The prognosis of perinatal infants is poor. During the period of expectant treatment, the maternal fetus should be closely monitored. Gestational weeks should be extended appropriately, and pregnancy should be terminated timely to improve neonatal survival rate.