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目的:探讨手足口病重症病例的临床特点,分析影响重症病例的关键因素,为疾病的预防及治疗提供科学依据。方法:回顾性研究我院2009年至2013年收治的304手足口病例,对其中65例重症病例进行分析。结果:65例重症病例组其中有3例重症病例死亡。Logistic风险回归分析影响重症HFMD的6项关键因素:年龄、发热持续时间、口腔疱疹、血液中性粒细胞计数、血红蛋白及血糖浓度(p<0.05)。结论:手足口病的早期诊断分型很重要,尤其对EV71病毒感染持续发热的患儿,结合试验室检查异常结果,早期判断积极治疗以降低病死率。
Objective: To investigate the clinical features of HFMD cases and to analyze the key factors influencing severe cases so as to provide a scientific basis for the prevention and treatment of the disease. Methods: A retrospective study of our hospital from 2009 to 2013 admitted 304 cases of mouth and mouth, of which 65 cases of severe cases were analyzed. Results: Three of 65 severe cases died of severe cases. Logistic risk regression analysis analyzed six key factors affecting severe HFMD: age, duration of fever, oral herpes, blood neutrophil count, hemoglobin and blood glucose levels (p <0.05). Conclusion: The early diagnosis of hand, foot and mouth disease is very important. Especially for children with persistent fever of EV71 virus infection, combined with abnormal results of laboratory tests, aggressive treatment should be judged early to reduce the mortality.