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丙型肝炎病毒的慢性感染是肝细胞癌发生的主要危险因素之一 ,核心蛋白在致癌过程中可能发挥了重要的作用。本文综述了近年来对丙型肝炎病毒核心蛋白特性及其相互作用蛋白的研究进展 ,尤其是针对核心蛋白与肝癌的发生和发展的关系作了较详细的探讨
Chronic hepatitis C virus infection is one of the major risk factors of hepatocellular carcinoma. Core protein may play an important role in carcinogenesis. This review summarizes recent advances in the properties and interaction proteins of hepatitis C virus core protein, in particular, the relationship between core protein and the occurrence and development of hepatocellular carcinoma