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目的:探讨盐酸米诺环素缓释抗菌软膏修复牙周牙髓联合病变效果分析,并总结临床经验。方法:本研究从2013年7月至2014年7月期间来我院口腔科进行治疗的牙周牙髓联合病变患者中,随机抽取80例,平均分为对照组和观察组。其中对照组采用碘甘油治疗。观察组采用盐酸米诺环素缓释抗菌软膏治疗。评价两组患者不同治疗后治疗有效率,分析盐酸米诺环素缓释抗菌软膏修复牙周牙髓联合病变效果。结果:观察组患者的治疗总有效率为97.57%,明显高于对照组(P<0.05),以上差异均具有统计学意义。结论:盐酸米诺环素缓释抗菌软膏治疗和修复牙周牙髓联合病变患者,在临床上具有良好的治疗效果,能够有效地改善患者牙龈炎症,降低龈沟出血概率,副作用少,不良事件发生率低,安全性高,值得临床推广应用。
Objective: To investigate the effect of minocycline hydrochloride sustained-release antimicrobial ointment on periodontal-pulp combined lesions and to summarize the clinical experience. Methods: From July 2013 to July 2014 in our hospital dental treatment of periodontal and endodontic patients with lesions, randomly selected 80 cases were divided into control group and observation group. The control group was treated with iodine glycerin. The observation group was treated with minocycline hydrochloride antibacterial ointment. Evaluation of two groups of patients after treatment efficiency, analysis of minocycline hydrochloride sustained-release antimicrobial ointment to repair periodontal and pulp joint lesions. Results: The total effective rate of the observation group was 97.57%, which was significantly higher than that of the control group (P <0.05). All the above differences were statistically significant. CONCLUSION: Minocycline hydrochloride sustained-release antibiotic ointment is effective in treating gingival inflammation, reducing the probability of bleeding in gingival sulcus, fewer side effects and adverse events in the treatment of patients with periodontal and pulp combined diseases. Low incidence, high safety, it is worth clinical application.