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作者报告1例毛细胞白血病并发何杰金病。患者56岁,男性,于1983年春发现左锁骨上淋巴结肿大,易出血、干咳,晚上出汗和低热,体温达100~101°F 约20年,在此期间报阿匹林可退热。体格检查有数个瘀斑,左锁骨上淋巴结肿大,最大为4×4.5cm,脾肿大至近左骨盆嵴及腹中线。白细胞计数为10,800/mm~3,分类毛细胞占27%,血小板计数35,000/mm~3。骨髓活检诊断为毛细胞白血病。1983年7月行脾切除,脾重3,000g,组织学检查为典型的毛细胞白血病的表现。曾用过消炎痛、瘤可宁,白细胞数降至正常,但淋巴结进行性肿大。1984年1月双侧颈部、锁骨上和腋窝淋巴结明显肿大,有数个超过3×3cm,质硬,固定,无压痛,肝达右肋下2 cm,直径12cm。左锁骨上淋巴结活检为何杰金
The authors report a case of hairy cell leukemia with Hodgkin’s disease. The patient, 56 years old, had a left supraclavicular lymphadenopathy, hemorrhage, dry cough, sweating and fever at night in the spring of 1983 and a body temperature of 100 to 101 ° F for about 20 years. During this period, aspirin was reported to be antipyretic. There are several physical examination ecchymosis, left supraclavicular lymph nodes, the largest 4 × 4.5cm, splenomegaly to the left pelvic crest and midline. White blood cell count was 10,800 / mm ~ 3, classification of hair cells accounted for 27%, platelet count 35,000 / mm ~ 3. Bone marrow biopsy diagnosis of hairy cell leukemia. July 1983 splenectomy, spleen weight 3,000g, histological examination of the typical performance of hairy cell leukemia. Have used indomethacin, tumor Ning, white blood cells dropped to normal, but progressive lymph node enlargement. January 1984 bilateral neck, supraclavicular and axillary lymph nodes were significantly enlarged, there are several more than 3 × 3cm, hard, fixed, no tenderness, liver right rib 2 cm, diameter 12cm. Left supraclavicular lymph node biopsy is why Jie Jin