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目的探讨未破裂输卵管妊娠给予米非司酮预处理后行腹腔镜保守性手术治疗的疗效。方法按纳入标准选取海南省中医院2010年1月～2011年6月期间收治的70例异位妊娠患者随机分成二组:实验组35例,先口服米非司酮150mg,每日2次,共2d,d3腹腔镜手术。对照组35例,予抗生素止血药,d3行腹腔镜手术,比较两组的疗效。结果实验组34例保守性手术成功,手术成功率97.1%,1例因手术中输卵管撕裂而行切除。对照组17例保守性手术成功,手术成功率48.6%,另18例均因输卵管病灶处渗血不止而行切除。实验组较对照组保守性手术成功率高,差异有统计学意义(P﹤0.05)。结论米非司酮预处理后再进行腹腔镜保守性手术治疗效果好,保留输卵管成功率高,能有效防止持续性异位妊娠的发生。
Objective To investigate the curative effect of laparoscopic conservative surgery after mifepristone preconditioning in unruptured tubal pregnancy. Methods Seventy patients with ectopic pregnancy who were admitted to Hainan Provincial Hospital of Traditional Chinese Medicine from January 2010 to June 2011 were randomly divided into two groups: experimental group (35 cases), first oral mifepristone (150 mg), twice daily, A total of 2d, d3 laparoscopic surgery. The control group of 35 patients given antibiotics hemostatic drugs, d3 laparoscopic surgery, the efficacy of the two groups were compared. Results In the experimental group, 34 cases of conservative surgery were successful. The success rate of operation was 97.1%. One case was removed due to the operation of tubal tearing. The control group of 17 cases of conservative surgery was successful, the success rate of 48.6% surgery, the other 18 cases were due to tubal bleeding at the lesion more than resection. The success rate of conservative surgery in the experimental group was significantly higher than that in the control group (P <0.05). Conclusions Mifepristone pretreatment followed by laparoscopic conservative surgery is good, and the success rate of retaining tubal is high, which can effectively prevent the occurrence of persistent ectopic pregnancy.