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虽然河南省于1926年首先在国内分离出羊种布氏菌,但布氏菌病(简称布病)的大面积防治及病原学研究还是建国后开始的。1953年我省主要布病疫区都不同程度地开展了布氏菌的调查研究,从而在病原学上确定了我省布病疫区的性质,掌握了布氏菌的种型及地区分布特点,同时还对贮菌宿主、宿主转移等作了相应的调查,并对分离的部分菌株的毒力、变异、交叉凝集等进行了测定。近年来,利用常规及分析微生物学技术开展了快速分型方法的研究。
Although Henan Province first isolated brucella in China in 1926, the large-scale prevention and pathogenic study of brucellosis (referred to as brucellosis) started after the founding of the People’s Republic of China. In 1953, the main brucellosis areas in our province carried out the investigation and study of brucellosis to varying degrees, thus etiologically determining the nature of the epidemic disease area in our province, mastering the species and geographical distribution characteristics of brucellosis, meanwhile In addition, host strains and host metastases were also investigated. The virulence, mutation and cross-aggregation of some isolates were also determined. In recent years, the use of conventional and analytical microbiology techniques to carry out rapid typing method.