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在急性心肌梗塞后,缩小梗塞面积及减轻缺血程度是目前国内、外临床及实验性研究的重点课题之一,而再灌是改善梗塞灶供血的方法之一,其中反搏术近来得到了重视,但其改善冠脉血供的效应并不理想,而且技术操作复杂,难以推广。为此,我们采用了不同溶液动脉加压逆行灌注法,来达到再灌的目的,以期观察其对实验性急性心肌梗塞的影响。在全麻开胸的条件下,直视结扎狗的冠状动脉前降支远侧端及左旋支的分支,造成心
In acute myocardial infarction, to reduce the infarct size and reduce the degree of ischemia is the current domestic and international clinical and experimental study of one of the key issues, and reperfusion is to improve the infarction of the blood supply method, in which counterpulsation has recently been Attention, but its effect of improving coronary blood supply is not ideal, and the technical operation is complex and difficult to promote. To this end, we used a different solution of arterial pressure retrograde perfusion method to achieve the purpose of reperfusion in order to observe its impact on experimental acute myocardial infarction. Under general anesthesia thoracotomy conditions, direct ligation of the dog’s anterior descending coronary artery distal branch and left branch, causing the heart