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严重呼吸机能不全,以成人呼吸窘迫综合征(ARDS)为多。著者研究1985～1987年行消化道手术后并发 ARDS42例,发现平均年龄65.1岁,急救17例,死亡率为59.5%。恶性肿瘤术后并发缝合不全、腹腔脓肿等重症感染也易发生 ARDS。42例中26例(62%)与感染有关,手术时间长,侵袭大常发生ARDS,长期呼吸管理的病人预后不佳。术后并发 ARDS 的机制和病理生理:ARDS 的诱因主要是感染,其次为休克、胸腹腔大手术、DIC 等。这些因素还可同时引起肝、肾、心等多脏器衰竭(M-OF)。重症感染引起 ARDS 系感染灶产生细菌毒素,局部组织破溃产生的物质与机体免疫及炎症反应有
Severe respiratory insufficiency, mostly adult respiratory distress syndrome (ARDS). The authors studied from 1985 to 1987 after the operation of gastrointestinal tract ARDS42 cases, found that the average age of 65.1 years, 17 cases of emergency, the mortality rate was 59.5%. Postoperative complications of malignant sutures, abdominal abscess and other severe infections are also prone to ARDS. Twenty-six of 42 patients (62%) were associated with infection, had a long period of surgery, had a high prevalence of ARDS, and had poor long-term respiratory management. Postoperative complications and pathophysiology of ARDS: The main causes of ARDS infection, followed by shock, thoracoabdominal surgery, DIC and so on. These factors can also cause liver, kidney, heart and other multiple organ failure (M-OF). ARDS infection caused by severe infection bacterial focus toxins, local tissue ulceration substances and the body caused by immune and inflammatory response